Significance of GlycolysisProduce ATPsProvide biosynthetic materialsMoonlighting functionGlycolysis and CancerHypoxia and hyoxia-inducible factorGlycolysis Provides biosynthetic materials Regulation o
Function of the TCA CycleProduces More ATPsAs a source of biosynthetic precursors Amon final metabolic pathway for glucose, aas and fatty acidsSome Immediates act as effectors to regulate other me
Chapter 4Tricarboxylic acid cycle三羧酸循环 (糖代谢Ⅱ) 三羧酸循环不仅是糖、脂肪、氨基酸等化合物生物氧化的共同通路,同时也为各种生物合成提供前体,成为各代谢途径连接的枢纽。TCA cycle is the hub of intermediary metabolism serving both the catabolic and anabolic proces
单击此处编辑母版标题样式单击此处编辑母版文本样式第二级第三级第四级第五级 第四节 三羧酸循环 概念:在有氧的情况下葡萄糖酵解产生的丙酮酸氧化脱羧形成乙酰CoA乙酰CoA经一系列氧化脱羧最终生成C2O和H2O并产生能量的过程称为柠檬酸循环亦称为三羧酸循环(tricarboxylic acid cycle) 简称TCA循环由于它是由H.A.Krebs(德国)正式提出的所以又称Krebs循环 三羧酸
第九章三羧酸循环Tricarboxylic Acid Cycle第二篇物质代谢与能量代谢乙酰CoATCA循环2H呼吸链 H2OADP+PiATPCO2* 营养物在生物体内氧化的一般过程在真核生物,TCA循环在线粒体中进行,与呼吸链在功能和结构上相偶联。第 一 节 三羧酸循环的概念及其发现史Concept and Scientific History of Tricarboxylic Aci
Chapter22GlycolysisOutlineOverview of GlycolysisAll glycolysis reactionsFates of NADH and PyruvateIn the presence of O2In the absence of O2How other substances other than glucose enter the glycolysisP
单击此处编辑母版标题样式单击此处编辑母版文本样式第二级第三级第四级第五级 第四节 三羧酸循环(TCA) 三羧酸循环的概念: 1937年德国生物学家Krebs (克雷布斯1953年因此获诺贝尔奖)阐明:乙酰CoA的继续分解是一个环式反应体系起点是乙酰CoA与草酰乙酸结合为具有三个羧基的柠檬酸故称为三羧酸循环(tricarboxylic acid)又叫TCA循环Krebs循环由于该
糖脂肪氨基酸生物氧化的三个阶段HNAD(P):electron carrierA model of the E. coli pyruvate dehydrognaseplex showing the three kinds of enzymes and the flexible lipoamide arms covalently attached to TCA 反应过程The first
Chapter 4Tricarboxylic acid cycle三羧酸循环 (糖代谢Ⅱ) 三羧酸循环不仅是糖、脂肪、氨基酸等化合物生物氧化的共同通路,同时也为各种生物合成提供前体,成为各代谢途径连接的枢纽。TCA cycle is the hub of intermediary metabolism serving both the catabolic and anabolic proces
The TCA CycleAmon metabolic pathway for glucose, aa and fatty acidaka Citric Acid Cycle, Krebs Cycle Pyruvate (actually acetate) from glycolysis is degraded to CO2 Some ATP is produced More NADH
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